• Supports healthy joint function
• Helps relieve pain
Maxi-Boz contains Boswellia serrata, an herb traditionally used in Ayurvedic medicine to deal with inflammatory disorders. Boswellic acids are phytonutrients that are useful for balancing inflammation, supporting joint function, reducing pain, and relieving arthritic conditions.
Put out the fires
Boswellia functions in a similar way as non-steroidal anti-inflammatory drugs that are generally used in inflammatory conditions. However, boswellic acids are less toxic and even more potent. They are effective at blocking the production of pro-inflammatory signaling molecules which cause the constriction of airways in the lungs. One of these signaling molecules is elastase, which may be involved in emphysema and possibly in cystic fibrosis, chronic bronchitis and acute respiratory distress syndrome. Boswellic acids also block the recruitment of inflammatory cells, and the increased permeability of blood vessels, which allow inflammatory cells to reach tissues. Boswellic acids also specifically inhibit the enzyme that is responsible for producing a main category of pro-inflammatory molecules.
Maxi-Boz contains standardized Boswellia serrata to prevent and alleviate the damages caused by excessive inflammation and reduce the symptoms of inflammatory disorders such as arthritis, ulcerative colitis, and many others.
There are many medicinal plants of great therapeutic value referred to in the ancient treatment system of Ayurveda. One particular plant of much repute is resin of the tree Boswellia serrata (BSE), or Frankincense, which the Ayurved materia medica claimed to have potent anti-inflammatory and anti-arthritic properties.
Ethanolic extracts of the resin demonstrated reduced paw swelling in rats and mice. Further, extracts showed anti-arthritic activity in arthritis in rats and rabbits. In addition, the researchers found the above extract to be more beneficial, less toxic and more potent than the standard drug of choice, Ketoprofen, a widely used prescriptive non-steroidal anti-inflammatory drug (NSAID). More recently, a number of researchers have identified the anti-inflammatory activity of the ethanolic extracts of the resin to be due to Boswellic Acids, in particular the alpha and beta isomers. Recently, a more purified compound standardized for 65% Boswellic Acids has shown potent anti-inflammatory and anti-arthritic activity without any of the adverse effects (e.g. gastro-intestinal, CNS and cardiovascular).
The mechanism of action of Boswellic Acids is similar to the action of NSAIDs. Prostaglandins and leukotrienes are two classes of inflammatory mediators. Leukotrienes, for which 5-lipooxygenase (5-LOx) is the key enzyme in synthesis, are considered to be involved in the initiation and maintenance of various inflammatory diseases, for example arthritis, Crohn's disease, ulcerative colitis, asthma etc. Boswellic Acids are potent inhibitors of 5-lipooxygenase products. Other anti-inflammatory plant constituents, such as quercetin, also block this enzyme, but they do so in a more general fashion, as an antioxidant, whereas Boswellia seems to be a specific inhibitor of 5-LOx.
It is known that non-steroidal anti-inflammatory drugs can cause a disruption of glycosaminoglycan (GAG) synthesis, which is required for joint and cartilage repair. This can accelerate the articular damage in arthritic conditions. A recent in-vivo study examined BSE and ketoprofen for their effects on glycosaminoglycan metabolism. BSE significantly reduced the degeneration of GAGs compared to controls, whereas ketoprofen caused a reduction in total tissue GAG content.
In addition, Boswellic Acids inhibited antibody production, as well as infiltration of leucocytes, thereby reducing the inflammatory effect. In conclusion there is considerable research to support the highly beneficial properties of standardized Boswellic Acids in inflammatory conditions.
BSE also demonstrated a marked inhibitory effect on both the classical and alternate complement systems, which are other pathways of inflammation.
An investigation of BSE's analgesic and psychopharmacologic effects noted that it "was found to exhibit marked sedative and analgesic effects" in animals.
Inflammatory Bowel Syndrome (IBS)
Leukotrienes are suggested to play a role in the inflammatory process of ulcerative colitis. BSE was comparable to sulfasalazine, a standard prescriptive drug in ulcerative colitis.
Other biological activities
BSE has also been observed to inhibit human leukocyte elastase (HLE), which may be involved in the pathogenesis of emphysema. HLE also stimulates mucus secretion and thus may play a role in cystic fibrosis, chronic bronchitis, and acute respiratory distress syndrome.
|Ingredients|| Contains: 90 Vegi-Caps
Serving Size: 1 Capsule
Amount per Serving:
AOR guarantees that no ingredients not listed on the label have been added to the product. Contains no wheat, gluten, corn, nuts, dairy, soy, eggs, fish or shellfish.
Suggested Use: Take one or two capsules three times a day, or as directed by a qualified health care practitioner.
Source: Boswellia serrata is a branching tree generally found in dry, hilly areas of India.
Pregnancy / Nursing: No studies have been conducted. Best to avoid.
Cautions: None known.
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