Details
• Promotes relaxation during times of stress
• Reduces Anxiety
• Increases growth hormone levels
• Helps prevent insomnia
The Brain’s Chemical Messengers
Neurotransmitters are chemical messengers that are responsible for transmitting signals from one nerve cell to another, especially in the brain. These messengers modulate and control a large number of functions in the body, including sleep, excitement, mood and memory. GABA is the most important inhibitory neurotransmitter in the brain. GABA acts like a “brake” during times of stress or anxiety, regulating brain excitability and inducing relaxation.
Rest and Relaxation
Research has shown that supplementation with GABA is beneficial for a large number of mood disorders. GABA has been used to address the symptoms of anxiety, depression, premenstrual dysphoric disorder and manic-depressive (bipolar affective) disorder. Additionally, GABA has been shown to be an effective solution for individuals suffering with insomnia, and can also act to increase growth hormone levels in the blood.
Potential Help for Epilepsy
In addition to mood disorders, GABA has also been studied for its potential benefit for individuals with disorders linked to overstimulation of the brain's motor centers, like epilepsy. Many drugs for the treatment of epileptic seizures actually enhance the levels of GABA in the brain or mimic its effects. As such, supplementation with GABA itself may help to reduce the frequency of epileptic seizures.
Neurotransmitters are like tiny messengers in the brain, transmitting signals from one neuron to another and modulating a huge number of functions in the human body, including sleep, mood, excitability, memory and relaxation. Imbalances in neurotransmitter levels can result in serious health problems including Parkinson’s disease, depression and other mood disorders.
Gamma-aminobutyric acid or GABA is the most important inhibitory neurotransmitter in the brain. GABA therefore acts as an inhibitor of nerve impulses or signals between neurons in the human brain and spinal cord, effectively creating a ‘calming effect’ by preventing the overstimulation of the brain. For example, during times of stress, GABA acts to regulate brain excitability, promoting a relaxed state and preventing anxiety. GABA receptors are highly concentrated in the thymus; the region of the brain associated with sleep. GABA is effective against a variety of central nervous system disorders, and has been shown to affect the brain directly, increasing alpha-brain waves (those associated with relaxation) and reducing beta-brain waves (those associated with anxiety and stress).
Research with GABA supplementation has focused on addressing conditions of anxiety, growth hormone deficiency, depression, epilepsy, and various other disorders of the central nervous system. In the early 1980’s, researchers believed that manipulating GABA receptors could alleviate the symptoms of anxiety, and supplementation with GABA itself was one such form of manipulation. This conclusion has since been strengthened by numerous studies confirming a direct correlation between major depressive disorder (MDD) and significantly decreased GABA concentrations in the occipital cortex of MDD subjects. This well-established correlation has led to the use of supplemental GABA as a means of addressing not only the symptoms of anxiety, but also of depression, premenstrual dysphoric disorder and manic-depressive (bipolar affective) disorder. The strategy is relatively straightforward; GABA inhibits the production of excitatory impulses from reaching the brain, including those that enhance panic, alarm, and/or fear. Anti-anxiety drugs such as benzodiazepine that are normally prescribed for such conditions can become addictive, a risk that is non-existent with GABA supplementation. Indeed, some research even supports using GABA to facilitate withdrawal from benzodiazepine medications.
In addition to mood disorders, GABA research has also been applied to the study of epilepsy, particularly in regard to how GABA supplementation can reduce the frequency and intensity of seizures. GABA is the major inhibitory neurotransmitter in the brain, and anticonvulsant drugs for the treatment of epileptic seizures are designed to enhance endogenous GABA levels (i.e. Vigabatrin) or mimic its effects (i.e. Gabapentin). This emphasis on maintaining high levels of GABA has once again led to the formularized justification of GABA supplementation, this time to offset epileptic seizures.
Finally, researchers have long believed that GABA can alleviate the symptoms of insomnia due to its ability to generate calm (via its inhibition of excitatory neural impulses) and thus induce sleep. The increase of plasma growth hormone (which also rises naturally during sleep) is yet another capability that has been attributed to exogenous GABA supplementation. This capability has made GABA a relative staple of the life-extensionist movement, which is always concerned with halting and/or reversing the inverse relationship between age and growth hormone levels. Research to support this exists in both human and animal studies, with one trial showing that a single 5-gram oral dose can raise growth hormone levels by as much as 550% within 90 minutes of ingestion. Elevated growth hormone levels play an important role in the prevention of a multitude of age-related conditions, including sarcopenia, metabolic syndrome, osteoporosis, and an overall impaired quality of life.
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MRM 5-HTP - 100 mg 60 vcaps
MRM 5-HTP - 50 mg 30 vcaps
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Natrol SAM-e - 200 mg 20 tabs
Natrol 5-HTP (50mg) - 60 caps
Natrol 5-HTP - 100 mg 30 caps
Natrol 5-HTP - 50 mg 30 caps
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Natrol 5-HTP TR - Time Release - 200 mg 30 tabs
Natrol Kava Kava - 200 mg 30 caps
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Natural Factors AdrenaSense - 120 vcaps
Natural Factors Suntheanine (L-theanine) (chewable) - 60 tabs
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Nature's Way B-Stress Formula - 100 caps
Nature’s Answer Oats - 30 ml
Nature’s Answer Relora - 60 caps
Nature’s Herbs St John's - Power 0.3% - 180 caps
Nature’s Herbs Valerian Extract - Standardized - 60 caps
Nature’s Way 5-HTP - 50 mg 30 tabs
Nature’s Way 5-HTP - 50 mg 60 tabs
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Nature’s Way Rhodiola Rosea - 60 vcaps
Nature’s Way Slippery Elm Bark - 100 caps
Nature’s Way St. John's Wort (350 mg.) - 180 caps
Nature’s Way St. John's Wort - 350 mg 100 caps
Nature’s Way St. John's Wort - Standardized Extract - 90 caps
Nature’s Way Valerian - Standardized Extract - 90 caps
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New Chapter Rhodiola Force 300 - 30 vcaps
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Now 5-HTP - 200 mg 60 vcaps
Now 5-HTP - 50 mg 180 caps
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NOW Chewable GABA Orange - 90 chews
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Now GABA 500 mg with B-6 - 200 caps
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Now Kava Kava Extract - 2 fl.oz
Now Kava Kava Extract - 250 mg 120 caps
Now Kava Kava Extract - 250 mg 60 caps
Now L-Phenylalanine - Supports Positive Mood - 500 mg 120 capsules
Now L-Theanine Double Strength - 200 mg 60 vcaps
Now L-Theanine with Decaffeinated Green Tea - 90 Vcaps
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Now L-Tyrosine capsules - 500 mg 120 capsules
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Now Methyl B-12 - 1000 mcg 100 lozenges
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Now Passion Flower Extract - 350 mg 90 vcaps
Now Phosphatidyl Serine - Improves Brain Function - 100 mg 60 Vcaps
Now Relora - 120 vcaps
Now Relora - 60 vcaps
Now Rhodiola (Rhodiola rosea) - 500 mg 60 Vcaps
Now SAMe - 100 mg 30 tablets
Now SAMe - 200 mg 30 tabs
Now SAMe - 200 mg 60 tablets
Now SAMe - 400 mg 60 tabs
Now St John's Wort - 300 mg 100 capsules
Now St. John's Wort - 300 mg 250 caps
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Now Valerian Root - 500 mg 250 caps
Now Valerian Root Extract Liquid - 2 fl.oz
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Olympian Labs Calm - 90 caps
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Paradise Herbs St. John's Wort - 90 vcaps
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Peter Gillham Natural Calm Orange - 16 oz
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Peter Gillham Natural Calm Plus Calcium - 16 oz
Peter Gillham Natural Calm Plus Calcium - 8 oz
Peter Gillham Natural Calm Sweet Lemon - 16 oz
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Planetary Formulas Full Spectrum Rhodiola Rosea Ext. - 327 mg 30 tabs
Planetary Formulas Rehmannia Endurance - 637 mg 150 tabs
Planetary Formulas Stress Free - 810 mg 180 tabs
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Source Naturals GABA - 750 mg 90 caps
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Source Naturals GABA Calm Sublingual - Orange - 30 tabs
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Additional Information
| Product SKU | 624917014006 | |||
|---|---|---|---|---|
| Manufacturer | AOR | |||
| Form | No | |||
| Ingredients | Contains: 60 Vegi-Caps Serving Size: 1 Capsule Amount per Serving:
Suggested Use: Take one to two capsules daily without food, or as directed by a qualified health practitioner. Do not use if pregnant or nursing.
Main Applications Source: Pharmaceutical synthesis Cautions: None Known Pregnancy/Nursing: Do not use if pregnant or nursing |
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