Dehydroepiandrosterone (DHEA) regulates the body’s production of numerous hormones, including stress and sex hormones. The body produces DHEA from cholesterols in the gonads, inside body fat and skin, in the brain, and in the adrenal glands. DHEA is responsible for 75% of estrogen production in females and half of testosterone production in males.

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DHEA helps increase lean muscle mass, stimulates bone growth, and can burn fat. It can also maintain a positive emotional balance, assist with weight loss, and treat chronic conditions such as lupus. Bodybuilders often take DHEA supplements to boost testosterone levels and gain lean muscle mass and strength.

Regular exercise and a reduced caloric intake can stimulate the body’s production of DHEA. Studies have demonstrated that DHEA supplements can suppress lipid and cholesterol levels and may help decrease the risk of developing cardiovascular problems.

People who have low DHEA levels often experience age-related health problems, which can be corrected with DHEA supplementation. Supplementation with this substance can also treat adrenal insufficiency, leading to enhanced energy and strength, a better sex drive, and improved hormone levels in people who have compromised adrenal function.

Some studies have suggested that DHEA can decrease the effects of aging. This is likely because of its connection to the production of human growth hormone. However, it is still being researched for its ability to treat chronic fatigue, muscle weakness, sexual dysfunction, and skin aging.

The body produces the most DHEA between the ages of 7 and 30 years. DHEA levels peak during your twenties and then decline after age 30. This may be because the body produces less of it, or because it needs less of it as you age. Stress, alcohol, and caffeine can also diminish DHEA levels.

There are a few negative side effects associated with DHEA, including emotional changes, insomnia, headaches, acne, and hair growth. It may also lead to stunted growth in teens that are still growing. Women may also experience menstrual irregularities and decreased HDL levels. Pregnant women should not supplement with DHEA, and DHEA should not be combined with estrogen replacements.

High doses of DHEA may be dangerous and have been linked to liver damage and impaired natural DHEA production. Discuss DHEA supplements with a medical professional before use. High dosages may also be linked to some types of cancer.