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AOR Homocysteine+ - Prevents Cardiovascular Disease - 515 mg 100 tabs

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Quick Overview

• Protection against cardiovascular diseases
• Decreases dangerous levels of homocysteine
• Lowers the risk of cardiovascular disease
• Protects against damaged blood vessels
• Promotes recycling of homocysteine into useful products

AOR Homocysteine+ - Protection Against Cardiovascular Diseases

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A dangerous amino acid
Homocysteine is a byproduct of an important metabolic process called a methylation cycle. It is a derivative of the essential amino acid methionine, and can be recycled into useful products by adding methyl groups. Unfortunately, homocysteine is toxic at high levels. When it accumulates, it can damage bloods vessels and impede collagen formation, increasing the risk of cardiovascular disease.

Homocysteine control
In order to recycle homocysteine into useful products and prevent it from accumulating, other participants in the methylation cycle are required. The main cofactors are Vitamin B6, Vitamin B12 and folic acid. The process also requires methyl donors, such as trimethylglycine which is the most effective homocysteine lowering substance known. Unfortunately, most people do not get enough of these nutrients in their diets.

Protect your heart
is formulated to include all the cofactors and methyl donors needed to convert homocysteine into useful amino acids and reduce the risk of heart disease.

Protect yourself against elevated homocysteine levels
Homocysteine is a toxic amino acid. It is naturally produced in the body as a byproduct of several metabolic pathways, such as the metabolism of the amino acid methionine to produce essential nucleic acids, fats and high-energy bonds. When methionine looses a methyl group, homocysteine is produced. If homocysteine levels increase, blood vessels are damaged and collagen formation is impeded. There are two pathways in the human body that can lead to the elimination of homocysteine: it can be methylated to methionine or condensed into cysteine. The former process requires folate and vitamin B12, while the latter is vitamin B6 dependant.

Why is Homocysteine harmful?
Elevated blood levels of homocysteine (Hyperhomocysteinemia) have been associated with higher incidences of coronary artery disease and increased risk of mortality from cardiovascular diseases. Hyperhomocysteinemia is an independent factor for peripheral vascular, cerebrovascular and coronary heart disease. High homocysteine levels have a variety of injurious effects and are thought to damage blood vessel walls and lead to cardiovascular complications. Impairment in the conversion of homocysteine to cysteine might also lead to higher blood cholesterol levels because cysteine is required for the metabolism of cholesterol. It is also possible that the amino acid affects blood coagulation.

What causes elevated homocysteine levels?
Elevations can arise from genetic defects, or from poor consumption of nutritional factors involved in homocysteine metabolism, particularly vitamins B12, B6 and folic acid. Insufficient intake of folate, vitamin B12 and B6 are common in the elderly. However, even young, healthy adults who exercise have been found to have elevated levels of homocysteine.

• A study of over 1000 people showed that, as dietary folate intake decreases, homocysteine level, narrowing of arteries, heart attacks and death due to cardiac disease increase.

• It is estimated that over 40% of the population is not consuming enough folate to keep homocysteine levels low.

• Hyperhomocysteinemia is believed to cause 60% of peripheral vascular disease.

• The Physician's Health Study showed that men with higher homocysteine levels had a threefold risk of coronary events.

• Elevated homocysteine levels lead to structural defects in collagen and may play a role in osteoporosis. In vitro studies have demonstrated that homocysteine increases the activity of bone breaking cells, leading to bone resorption.

• Folic acid supplementation reduces homocysteine levels even if the individual is not folate deficient. Simple supplementation can reduce mild homocysteine elevation in virtually all cases. Folic acid supplementation is more effective than dietary folate at lowering homocysteine levels.

The value of AOR's Homocysteine+ was tested in a randomized, double-blind, controlled study from the University of East London. Participants who took Homocysteine+ had a significant decrease in their homocysteine levels regardless of their initial levels. Those whose initial levels of homocysteine were high enough to put them in the "at risk" category experienced a dramatic homocysteine drop, indicating that these participants reduced their risk of cardiovascular disease in only 6 weeks of supplementation.

How can homocysteine levels be reduced?
The enzymes that metabolize homocysteine into methionine and cysteine use folate, vitamin B12, and vitamin B6 as cofactors. Trimethylglycine is a methyl group donor and can reduce homocysteine plasma levels by as much as 30%. Trimethylglycine is the most effective homocysteine lowering substance known. AOR's Homocysteine + has been formulated to include the cofactors and methyl donors necessary for the methylation of homocysteine into other harmless amino acids.

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Additional Information

ProductSKU 624917041071
Ingredients Contains: 100 Tablets
Serving Size: 1 Tablet

Amount per Serving:

Vitamin B6 (pyridoxine HCL) 15 mg
Vitamin B12 (Cyanocobalamine) 250 mcg
Folic Acid 400 mcg
Trimethylglycine 400 mg

(click an ingredient to view description)

Non-medicinal ingredients:

microcrystalline cellulose, silicon dioxide, dicalcium phosphate, magnesium stearate.

AOR guarantees that no ingredients not listed on the label have been added to the product. Contains no wheat, gluten, corn, nuts, dairy, soy, eggs, fish, or shellfish.

Suggested Use: Take 1 tablet 3 times a day with meals or as directed by a qualified health care practitioner.

Main Applications
• Aging
• Elevated homocysteine levels
• Cardiovascular health
• Anti-inflammatory
• Osteoporosisc
• Macular degeneration
• Cancer

Source: Multi-Sourced

Pregnancy / Nursing: No studies, best to avoid.

Cautions: None.

Other Ingredients .
Directions .
Warning .

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