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AOR Mag Malate Renew - Alleviates Pain and Fatigue - 120 capsules

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Quick Overview

Alleviates pain and fatigue
• Reduces the symptoms of fibromyalgia and chronic fatigue syndrome
• Enhances cellular energy production
• Helps regulate nerve receptors involved in pain
• Required for muscle function

AOR Mag Malate Renew - Alleviates Pain and Fatigue

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Alleviates pain and fatigue
• Reduces the symptoms of fibromyalgia and chronic fatigue syndrome
• Enhances cellular energy production
• Helps regulate nerve receptors involved in pain
• Required for muscle function

The pain of fibromyalgia
Fibromyalgia is a condition whose symptoms include muscular pain and stiffness, aching, depression, sleep disturbances, and many others. It is generally characterized by low levels of the cellular energy compound, ATP, and by abnormalities in the cellular cycle that produces energy. Low ATP levels may contribute to muscle weakness and pain, and may cause a decline in cognitive function, which could explain the mental fog often experienced by fibromyalgia patients.

Magnesium and malic acid
Magnesium plays an essential role in energy production cycles, and it stabilizes ATP to prevent it from being degraded. It also helps with the regulation of nerve receptors that are involved in fibromyalgic pain. Malic acid is also important in the production of ATP. Its levels are increased during physical activity.

An energetic combination
Studies have found that the combination of magnesium and malic acid significantly reduces the symptoms of fibromyalgia. This combination may also be effective for relieving chronic fatigue syndrome. AOR's formula provides safe and effective relief for conditions of pain and fatigue.

Fibromyalgia is a common clinical syndrome of generalized muscular pain, stiffness and chronic aching. It is characterized by reproducible tenderness on palpitation of specific anatomical sites called tender points. Other symptoms include short term memory loss, forgetfulness, depression, sleep disturbances, mild fevers or chills, sore throat, and painful lymph nodes in the neck. White, middle aged (30- to 50-year old) women are much more likely to suffer fibromyalgia than are men.

When your body consumes food, it cannot use it directly, but must first convert it into a useable form of energy: adenosine triphosphate (ATP), the "univeral energy currency." Low levels of ATP, and abnormalities in the glycolytic cycle, are commonly found in people suffering with fibromyalgia, and are believed to play a significant role in the physical and mental symptoms of the disease. Restoring cellular ATP levels is therefore crucial to digging your way out of the pit of this debilitating disorder.

Magnesium and Energy Production
Magnesium plays a critical role in the production and stabilization of ATP. It activates almost all the enzymes of the glycolytic and the tricarboxylic acid (TCA) cycles, which transform fats and sugars into useable energy. Without magnesium, ATP is quickly broken down into the forms which cannot deliver energy. Magnesium is also needed for the very structure of mitochondria, the cell's "power plants:" magnesium defiency causes swelling and disruption of the cristae (the folds in the inner mitochondrial membrane, where oxidative phosphorylation of ADP into ATP occurs) and leads to a decreased number of mitochondria per cell. Maintaining adequate ATP levels is critical to brain function. The brain stores 20% of total body ATP. Low levels of ATP may cause a decline in cognitive function - the "brain fog" so commonly reported, in which victims find themselves struggling through a dark haze, unable to concentrate and often forgetting simple thoughts and tasks.

A lack of ATP is also thought responsible for the muscle weakness and pain that accompanies the disease. Here again, magnesium is crucial for adequate muscle metabolism and function. In magnesium deficiency, there is excessive muscle tension, leading to muscle spasms, restlessness, tics, and twitches. Also, studies have found that the tender points in fibromyalgia victims' muscles are deficient in ATP.

Malic Acid and Energy Production
Malic Acid has an important role in generation of mitochondrial ATP, both under aerobic and low-oxygen conditions. In animal experiments, malate has been shown to increase anaerobic (oxygen-free) endurance, as measured by increased swimming times. Malic acid is the only metabolite of the citric acid cycle which correlates positively with physical activity: experimental studies show that exercise-induced mitochondrial respiration is associated with increased malate levels only; other TCA metabolites remain unchanged. As well, malic acid is a potent aluminum chelator.

Magnesium and Malate in Fibromyalgia
Two open trials have reported significant reductions in measurements of myalgic pain, as assessed by tender point index, in fibromyalgia victims supplementing with magnesium and malic acid. The dosages have ranged from 300 to 600 mg of magnesium and 1200 to 2400 mg of malate, with most symptoms improving in approximately eight weeks.

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Additional Information

ProductSKU 624917040111
Manufacturer No
Form No
Ingredients Contains: 120 Vegi-Caps

Amount per Serving:

Magnesium Malate Trihydrate 870 mg
Magnesium (elemental) 100 mg
Malic Acid 525 mg

AOR guarantees that no ingredients not listed on the label have been added to the product. Contains no wheat, gluten, corn, nuts, dairy, soy, eggs, fish or shellfish.

Suggested Use: Take one to three capsules daily with food, or as directed by a qualified health consultant. Increase dosage gradually.

Main Applications
• Support in Chronic Fatigue Syndrome
• Support in fibromyalgia

Source: Pharmaceutical synthesis.

Pregnancy / Nursing: Safe

Cautions: None known.

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