Enzymatic Therapy® Remifemin is an estrogen-free supplement that acts as a natural safe substitute to hormone replacement therapy (HRT) for the symptoms of menopause. It can produce a reduction of up to 70% in hot flushes, night sweats, annoyance, impatience, mood swings and occasional restlessness and apprehension. More than fifty research studies have shown that the ingredients form a harmless but efficient substitute for HRT, and includes RemiSure™ black cohosh, which has been shown to be more efficient than traditional soy in easing menopausal problems. It has been recognized as an efficient supplement by several top health magazines such as Pilates Style and Better Nutrition.